Cosmetic innovation based on
Keratinase: a new approach to visible skin care
What is Smarkter?
Smartker is an innovative cosmetic line featuring recombinant Keratinase, designed to visibly improve the appearance and texture of the skin.
It combines professional-use and at-home formulas tailored to different aesthetic needs, skin types, and times of the year.
Thanks to its versatility, Smartker easily integrates into advanced cosmetic routines, making it an excellent option to complement topical care in professional settings.
About our Keratinase PB333
Keratinase PB333 is a biotechnologically developed enzyme created by pbserum, known for its high cosmetic specificity.
It is integrated into formulas designed to condition the skin and visibly improve its texture and appearance, while respecting its natural balance.
Its use in Smartker is part of an innovative cosmetic approach that combines science and advanced topical care.
Products
Professional Equilibrium & Daily Anti-Blemish
Chronoaging
Professional Multivit & Daily Oily Skin
Oily and/or acne-prone skin
Professional Radiant & Daily Radiant
Hyperpigmentation
Professional Hyaluronic & Daily Anti-Wrinkle
Loss of hydration
Professional Firmness & Daily Firmness
Loss of firmness
Results
No skin alterations.(1)
Up to a 30%(1)
improvement of the skin health.
> 85% (1) patients satisfied with the results after their smartker treatments.
Before/After
Hyaluronic
Author: Dr. Norma Reyes (Dominican Republic)
Equilibrium
Study results*
Multivit
Study results*
Radiant
Study results*
Firmness
Author: Yuvell clinic (Austria)
Doctor's opinion
"It is a clinically and dermatologically tested treatment that I have been using for many years, and both my patients and I are satisfied with the results."
"It is a non-invasive and innovative treatment that allows me to improve the health and appearance of all skin types, and I can easily combine it with other treatments in my practice."
Frequently
Asked
Questions
The aim of the smartker line is to combine the Professional treatment (applied by the physician) with the Daily treatment (applied by the patient). The active ingredients of each formula complement each other to achieve an improvement of the problem to be treated. The benefits of Professional can be maintained with the Daily home treatment. The patient will be treated with smartker Professional once a week for 5 weeks, and will be combined with Smartker Daily daily by the patient for 30 days.
The recommended protocol consists of applying smartker professional once a week for 5 weeks, combined with smartker daily every day at night during the treatment period, with visible results from the first application. As in various aesthetic procedures, the protocols can be adapted according to the patient’s profile, the clinical need to be treated and the physician’s assessment.
SmartKer is an ideal treatment for all skin types, all year round. It has been evaluated by dermatologists in patients with sensitive skin, with no adverse events. All products have a low immunogenic potential and are gentle on the skin.
SmartKer contains keratinase, whose mechanism of action consists of increasing the permeability and, up to 9 times more, the retention of the active ingredients. It acts on the corneodesmosomes, which are reestablished in 6 to 8 hours, leaving the skin without side effects and can be used at any time of the year and on all phototypes, without leaving an aesthetic trace. On the other hand, a chemical peel is a controlled destruction of the skin layers through different acids. This brings with it side effects such as peeling, aesthetic trace, anti-inflammatory hyperpigmentation, burns… so it should not be used on all skin phototypes and is limited to certain times of the year due to the prohibition of sun exposure.
Do not apply in areas with skin infection, folliculitis or chronic acne in the area. The product is not injectable and is not recommended during pregnancy and lactation.
It is recommended to do the complete treatment: 5 weekly sessions of smartker professional combined with smartker Daily, for home use, for 1 month. It is also a versatile product that offers 3 options: Combination between products of the smartker line, with the help of other apparatology and after finishing other procedures.
(1) Data on file. Vv_et-sc20dxt2(d)-a_001_23_001 v1 equilibrium; vv_et-sc20dxt2(d)-a_001_22_002 v1 multivit; vv_et-1620dxt3(d)-a_001_23_001 v3 hyaluronic; vv_et-9+20dxt2(d)-a_001_23_001 v1 extreme firmness; vv_et-320dxt3(d)-a_001_23_001 v1 radiant. 2023.
*Study: Effectiveness and safety of pbserum Multivit Professional® Data on File 2024.
*Smartker products are registered as topical-use cosmetic products in accordance with current European Union regulations.
They are not intended to prevent, treat, or cure dermatological conditions, nor to modify the physiological functions of the skin.
Any mention of ingredients, technologies, or professional routines is provided for informational purposes only and within the scope of cosmetic regulation.
Always follow the instructions for use and consult a professional if you have questions about proper application.